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              首頁 > 產品 > 病理抗體及試劑盒 > 免疫組化單克隆抗體

              Anti-human PCNA Mouse Monoclonal Antibody datasheet

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              數據表

              • 概述

                Anti-human PCNA mouse monoclonal antibody

                PCNA is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. PCNA blongs to the PCNA family. It’s cellular localization is nucleus. Forms nuclear foci representing sites of ongoing DNA replication and vary in morphology and number during S phase. Together with APEX2, is redistributed in discrete nuclear foci in presence of oxidative DNA damaging agents.

                IHC

                Human

                Recombinant protein of human PCNA.

              • 性能

                Liquid

                PCNA antibody is stable for 1 month at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles

                PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol

                0.2 mg/ml

                Mouse IgG

              • 應用

                IHC: 1/500-1/1000 Optimal dilutions/concentrations should be determined by the end user.

              • 圖像
                PCNA mouse mAb.jpg
                Immunohistochemistry Staining of Human colon cancer with PCNA mouse mAb.
              規格 價格

              ¥970.00

              ¥2814.00

              ¥4698.00

              貨號:PMA-0014
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